Chem-is-try

Do you know about biopolymer chitosan?

Before we touch chitosan, for the first I will give explanation about bioploymer.

Biopolymer consists of two words such as bio and polymer. The meaning of bio refer to organism/natural and the word of polymer have meaning the supramacromolecule that construct from a variant of monomer or combine of two or more monomer and it can have biggest weight of molecular. So, we can redefine biopolymer with the two words before, it have means naturally supramacromolecule (can be collect from organism/microorganism) that construct from a variant of monomer or combine of two or more monomer and it can have biggest weight of molecular.

Chitosan is the second most abundant natural polymer and has many useful applications in the area of biomedical engineering, including gene delivery, due to its cationic character at physiological conditions. Chitosan shows limited solubility at neutral pH, and forms polyelectrolyte complexes with polyanions, often resulting in precipitation. Chitosan  also has  been  used  as  a  support  for  enzyme  immobilization  (Klein  et  al.,  2012;  Kuo  et  al.,  2012;  Li,  Cai,  Zhong,  &  Du, 2012;  Muzzarelli,  1980;  Orrego  et  al.,  2010).  Chitosan,  isolated from  chitin,  is  the  linear  and  partly  acetylated  (1–4)-2-amino-2-deoxy--d-glucan  (Muzzarelli,  1977,  2012;  Muzzarelli  et  al.,  2012). Chitosan is a cationic natural copolymer of glucosamine and biodegradable mucoadhesive polysaccharide derived from crustacean shells. Chitosan particles have been shown to increase transcellular and paracellular transport of macromolecules across the intestinal epithelial monolayer andused successfully todeliver adrugorally toenterocytes, Peyer’s patches and mesenteric lymph nodes (Desai et al., 1996; vanderLubbenet al., 2001;Ouji et al., 2002). Chitosan has been used widely for the production of biodegradable and biocompatible micro- and nanoparticles.